Optical Control of Peroxisomal Trafficking
نویسندگان
چکیده
منابع مشابه
Optical Control of Peroxisomal Trafficking
The blue-light-responsive LOV2 domain of Avena sativa phototropin1 (AsLOV2) has been used to regulate activity and binding of diverse protein targets with light. Here, we used AsLOV2 to photocage a peroxisomal targeting sequence, allowing light regulation of peroxisomal protein import. We generated a protein tag, LOV-PTS1, that can be appended to proteins of interest to direct their import to t...
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متن کاملPeroxisomal disorders: the single peroxisomal enzyme deficiencies.
Peroxisomal disorders are a group of inherited diseases in man in which either peroxisome biogenesis or one or more peroxisomal functions are impaired. The peroxisomal disorders identified to date are usually classified in two groups including: (1) the disorders of peroxisome biogenesis, and (2) the single peroxisomal enzyme deficiencies. This review is focused on the second group of disorders,...
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ژورنال
عنوان ژورنال: ACS Synthetic Biology
سال: 2015
ISSN: 2161-5063,2161-5063
DOI: 10.1021/acssynbio.5b00144